Multiple primary cutaneous melanomas
نویسندگان
چکیده
منابع مشابه
Multiple Primary Acral Lentiginous Melanomas (MPALM)
We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolat...
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It has been observed that a patient’s “normal” moles resemble each other clinically. This concept also applies to dermoscopic observations, as shown by our previous demonstration that an individual’s nevi tend to have one to three predominant overall dermoscopic patterns [1]. A recent study investigated and compared the dermoscopic patterns of multiple primary melanomas (MPMs) in a large series...
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A 66-year-old Japanese man presented with a painless skin tumor in his left axillae which had been present for several years without receiving any medical treatment. The tumor enlarged and lesions appeared on several areas on his body within a few months of April 2012 (Fig. 1). Histopathological examination of a skin biopsy specimen taken from a right inguinal tumor showed a dense infiltrate of...
متن کاملCDKN2A germ-line mutations in individuals with multiple cutaneous melanomas.
Germ-line CDKN2A mutations are present in some kindreds with hereditary cutaneous melanoma, and in Sweden a founder mutation with an extra arginine in codon 113 (113insR) has been identified. We screened 80 individuals with at least two primary cutaneous melanomas, who were identified mainly by a search of a regional cancer registry, for germ-line CDKN2A mutations. In nine patients, CDKN2A alte...
متن کاملMultiple cutaneous melanomas associated with gastric and brain metastases*
The occurrence of multiple primary melanomas in a single individual is rare. Most commonly, malignant melanocytic lesions subsequent to the initial diagnosis of melanoma are secondary cutaneous metastases. We report a patient with gastrointestinal bleeding from gastric metastasis of cutaneous melanoma. During clinical evaluation and staging, we discovered a brain metastasis associated with 3 sy...
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ژورنال
عنوان ژورنال: Cancer
سال: 1992
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19921001)70:7<1911::aid-cncr2820700718>3.0.co;2-q